Experimental venous thrombus resolution is driven by IL-6 mediated monocyte actions

Abstract Deep venous thrombosis and residual thrombus burden correlates with circulating IL-6 levels in humans. To investigate the cellular source and role of IL-6 in thrombus resolution, Wild type C57BL/6J (WT), and IL-6−/− mice underwent induction of VT via inferior vena cava (IVC) stenosis or sta...

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Bibliographic Details

Published in:	Scientific Reports
Main Authors:	Andrea T. Obi, Sriganesh B. Sharma, Megan A. Elfline, Catherine E. Luke, Abigail R. Dowling, Qing Cai, Andrew S. Kimball, Mike Hollinstat, Livia Stanger, Bethany B. Moore, Farouc A. Jaffer, Peter K. Henke
Format:	Article
Language:	English
Published:	Nature Portfolio 2023-02-01
Online Access:	https://doi.org/10.1038/s41598-023-30149-2