HLA Does Not Impact on Short-Medium-Term Antibody Response to Preventive Anti-SARS-Cov-2 Vaccine

The response to anti-SARS-Cov-2 preventive vaccine shows high interpersonal variability at short and medium term. One of the explanations might be the individual HLA allelic variants. Indeed, B cell response is stimulated and sustained by CD4+ T helper cells activated by antigens presented by HLA-cl...

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Bibliographic Details

Published in:	Frontiers in Immunology
Main Authors:	Concetta Ragone, Serena Meola, Pasqualina C. Fiorillo, Roberta Penta, Laura Auriemma, Maria Lina Tornesello, Leonardo Miscio, Ernesta Cavalcanti, Gerardo Botti, Franco M. Buonaguro, Attilio Bianchi, Luigi Buonaguro, Maria Tagliamonte
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2021-07-01
Subjects:	SARS-CoV-2 HLA-DQ antigens BNT162b2 mRNA COVID-19 vaccine antibody titer level HLA-DR antigens
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2021.734689/full