Internal translation of Gja1 (Connexin43) to produce GJA1-20k: Implications for arrhythmia and ischemic-preconditioning

Internal translation is a form of post-translation modification as it produces different proteins from one mRNA molecule by beginning translation at a methionine coding triplet downstream of the first methionine. Internal translation can eliminate domains of proteins that otherwise restrict movement...

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Bibliographic Details

Published in:	Frontiers in Physiology
Main Authors:	Claire C. Whisenant, Robin M. Shaw
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-12-01
Subjects:	GJA1-20k Connexin43 mitochondria ischemia reperfusion ischemic precondioning
Online Access:	https://www.frontiersin.org/articles/10.3389/fphys.2022.1058954/full