Taurine depletion during fetal and postnatal development blunts firing responses of neocortical layer II/III pyramidal neurons

Fetal and infant brains are rich in maternally derived taurine. We previously demonstrated that taurine action regulates the cation-chloride cotransporter activity and the differentiation and radial migration of pyramidal neuron progenitors in the developing neocortex of rodent fetuses. Here we exam...

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Bibliographic Details

Published in:	Frontiers in Molecular Neuroscience
Main Authors:	Yasushi Hosoi, Tenpei Akita, Miho Watanabe, Takashi Ito, Hiroaki Miyajima, Atsuo Fukuda
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-11-01
Subjects:	taurine neocortex pyramidal neurons action potentials taurine transporter-knockout mouse
Online Access:	https://www.frontiersin.org/articles/10.3389/fnmol.2022.806798/full