Epigenetic Mechanisms Governing Nrf2 Expression and Its Role in Ferroptosis

Ferroptosis is a distinct form of regulated cell death driven by iron-dependent lipid peroxidation participating in various diseases. The nuclear factor erythroid 2-related factor 2 (Nrf2) is a central regulator of cellular redox homeostasis and a key determinant of ferroptosis resistance. Nrf2 acti...

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Bibliographic Details

Published in:	Biomedicines
Main Authors:	Linbo Li, Xinjun Liu, Zizhen Si, Xidi Wang
Format:	Article
Language:	English
Published:	MDPI AG 2025-08-01
Subjects:	ferroptosis Nrf2 epigenetics DNA methylation histone modification non-coding RNAs
Online Access:	https://www.mdpi.com/2227-9059/13/8/1913