Pyk2 Regulates MAMs and Mitochondrial Dynamics in Hippocampal Neurons

Pyk2 is a non-receptor tyrosine kinase enriched in hippocampal neurons, which can be activated by calcium-dependent mechanisms. In neurons, Pyk2 is mostly localised in the cytosol and dendritic shafts but can translocate to spines and/or to the nucleus. Here, we explore the function of a new localis...

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Bibliographic Details

Published in:	Cells
Main Authors:	Laura López-Molina, Joaquín Fernández-Irigoyen, Carmen Cifuentes-Díaz, Jordi Alberch, Jean-Antoine Girault, Enrique Santamaría, Silvia Ginés, Albert Giralt
Format:	Article
Language:	English
Published:	MDPI AG 2022-03-01
Subjects:	hippocampus calcium ER-mitochondria contact sites neuron
Online Access:	https://www.mdpi.com/2073-4409/11/5/842