Macrophage-mimetic liposomes co-delivering ceria and Ac2-26 peptide for penumbra protection in ischemic stroke

Abstract Ischemic stroke is one of the most severe central nervous system disease with high disability and mortality rates worldwide. Effective treatment requires strategies that address the multifaceted pathophysiology of ischemic penumbra, including oxidative stress-induced neuronal apoptosis and...

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Bibliographic Details

Published in:	Journal of Nanobiotechnology
Main Authors:	Lingyun Bai, Na Li, Huiqin Li, Yuxuan Dai, Yi Bai, Feiyu Ma, Dujuan Sha, Shengnan Xia, Yun Xu, Xiang Cao
Format:	Article
Language:	English
Published:	BMC 2025-07-01
Subjects:	Macrophage membrane Ceria Ischemic stroke Neurons Blood-brain barrier Reactive oxygen species
Online Access:	https://doi.org/10.1186/s12951-025-03575-9