Baseline and three-month De Ritis ratio and gamma-glutamyltransferase as prognostic biomarkers in metastatic renal cell carcinoma treated with targeted therapy

Abstract Liver function tests (LFTs)–derived parameters such as the De Ritis ratio (DRR) and gamma-glutamyltransferase (GGT) may reflect tumor biology and systemic inflammation. Thus, we evaluated both baseline and 3-month measurements of LFTs in patients with metastatic renal cell carcinoma (mRCC)...

Full description

Bibliographic Details

Published in:	Scientific Reports
Main Authors:	Oktay Halit Aktepe, Tugce Ulasli, Ilkay Tugba Unek, Elif Atag, Huseyin Salih Semiz, Aziz Karaoglu, Mustafa Erman, Suayib Yalcin
Format:	Article
Language:	English
Published:	Nature Portfolio 2026-03-01
Subjects:	De Ritis ratio GGT Liver function tests Metastatic renal cell carcinoma Gamma-glutamyltransferase
Online Access:	https://doi.org/10.1038/s41598-026-43971-1