Beyond the VSG layer: Exploring the role of intrinsic disorder in the invariant surface glycoproteins of African trypanosomes.

In the bloodstream of mammalian hosts, African trypanosomes face the challenge of protecting their invariant surface receptors from immune detection. This crucial role is fulfilled by a dense, glycosylated protein layer composed of variant surface glycoproteins (VSGs), which undergo antigenic variat...

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Bibliographic Details

Published in:	PLoS Pathogens
Main Authors:	Hagen Sülzen, Alexander N Volkov, Rob Geens, Farnaz Zahedifard, Benoit Stijlemans, Martin Zoltner, Stefan Magez, Yann G-J Sterckx, Sebastian Zoll
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2024-04-01
Online Access:	https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1012186&type=printable