Functional, transcriptomic, and lipidomic studies of the choC gene encoding a phospholipid methyltransferase in Aspergillus fumigatus

ABSTRACT Phosphatidylcholines (PCs) are a class of cell membrane phospholipids playing important roles in cellular integrity and signaling. In eukaryotes, PCs are biosynthesized via the Kennedy cytidine nucleotide and the Bremer-Greenberg pathways. The Aspergillus choC gene is predicted to encode a...

Full description

Bibliographic Details

Published in:	Microbiology Spectrum
Main Authors:	Jiao Pan, Xinyu Yang, Cuiting Hu, Tongtong Fu, Xiuyan Zhang, Zijun Liu, Yu Wang, Fengyu Zhang, Xiaoyuan He, Jae-Hyuk Yu
Format:	Article
Language:	English
Published:	American Society for Microbiology 2024-01-01
Subjects:	phosphatidylcholines Aspergillus fumigatus ChoC transcriptomics lipidomics
Online Access:	https://journals.asm.org/doi/10.1128/spectrum.02168-23