IL-1β but not programmed death-1 and programmed death-ligand pathway is critical for the human Th17 response to M. tuberculosis

The programmed death-1 (PD-1)- programmed death ligand-1 (PD-L1) and PD-L2 co-inhibitory pathway has been implicated in the evasion strategies of Mycobacterium tuberculosis. Specifically, M. tuberculosis-induced PD-L1 orchestrates expansion of regulatory T cells (Tregs) and suppression of Th1 respon...

詳細記述

書誌詳細

出版年:	Frontiers in Immunology
主要な著者:	Emmanuel Stephen-Victor, Varun Kumar Sharma, Mrinmoy Das, Anupama Karnam, chaitrali Saha, Maxime Lecerf, Caroline Galeotti, Srinivas Kaveri, Jagadeesh BAYRY
フォーマット:	論文
言語:	英語
出版事項:	Frontiers Media S.A. 2016-11-01
主題:	Dendritic Cells Monocytes Mycobacterium tuberculosis T cells IL-23 Th17
オンライン･アクセス:	http://journal.frontiersin.org/Journal/10.3389/fimmu.2016.00465/full