History and Evolution of the Hypervirulent <i>Clostridioides difficile</i> Ribotype 027 Lineage

<i>Clostridioides difficile</i> was first identified in 1935 and subsequently emerged over the next several decades as the predominant bacterial cause of healthcare-associated gastrointestinal infections, placing a significant burden on healthcare systems worldwide. A major driver of the...

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Bibliographic Details

Published in:	Microorganisms
Main Authors:	Isabella A. Tickler, Richard V. Goering, Fred C. Tenover
Format:	Article
Language:	English
Published:	MDPI AG 2025-10-01
Subjects:	<i>Clostridioides difficile</i> glucosylating toxins binary toxin ribotyping pathogenesis
Online Access:	https://www.mdpi.com/2076-2607/13/10/2376