History and Evolution of the Hypervirulent <i>Clostridioides difficile</i> Ribotype 027 Lineage

<i>Clostridioides difficile</i> was first identified in 1935 and subsequently emerged over the next several decades as the predominant bacterial cause of healthcare-associated gastrointestinal infections, placing a significant burden on healthcare systems worldwide. A major driver of the...

وصف كامل

التفاصيل البيبلوغرافية
الحاوية / القاعدة:	Microorganisms
المؤلفون الرئيسيون:	Isabella A. Tickler, Richard V. Goering, Fred C. Tenover
التنسيق:	مقال
اللغة:	الإنجليزية
منشور في:	MDPI AG 2025-10-01
الموضوعات:	<i>Clostridioides difficile</i> glucosylating toxins binary toxin ribotyping pathogenesis
الوصول للمادة أونلاين:	https://www.mdpi.com/2076-2607/13/10/2376

مواد مشابهة

High Prevalence of <i>Clostridioides difficile</i> Ribotype 176 in the University Hospital in Kosice
حسب: Katarina Curova, وآخرون
منشور في: (2023-03-01)

Biological characteristics associated with virulence in Clostridioides difficile ribotype 002 in Hong Kong
حسب: Ka Yi Kong, وآخرون
منشور في: (2020-01-01)

Usefulness of Capillary Gel Electrophoresis-Based PCR for Detection of <i>Clostridioides difficile</i> Strains with Hypervirulent Ribotypes
حسب: Tomasz Bogiel, وآخرون
منشور في: (2024-05-01)

Whole genome sequence analysis reveals limited diversity among Clostridioides difficile ribotype 027 and 078 isolates collected in 22 hospitals in Berlin and Brandenburg, Germany
حسب: Esther E. Dirks, وآخرون
منشور في: (2025-05-01)

Characterization of Food Chain <i>Clostridioides difficile</i> Isolates in Terms of Ribotype and Antimicrobial Resistance
حسب: Pilar Marcos, وآخرون
منشور في: (2023-05-01)

Molecular epidemiology and antimicrobial resistance patterns of Clostridioides difficile isolates in Algerian hospitals
حسب: Youcef Boudjelal, وآخرون
منشور في: (2022-06-01)

Emerging Clostridioides difficile ribotypes have divergent metabolic phenotypes
حسب: Firas S. Midani, وآخرون
منشور في: (2025-03-01)

The Molecular Epidemiology of <i>Clostridioides difficile</i> Infection in Central India: A Prospective Observational Cohort Study
حسب: Rima Biswas, وآخرون
منشور في: (2023-09-01)

Antibiotic Resistance Profile of RT 027/176 Versus Other <i>Clostridioides difficile</i> Isolates in Silesia, Southern Poland
حسب: Małgorzata Aptekorz, وآخرون
منشور في: (2022-08-01)

Risk factors for Clostridioides difficile infection caused by ribotype 027 strains in the Veterans Affairs Healthcare System: a matched case-control study
حسب: Sandra Y. Silva, وآخرون
منشور في: (2025-05-01)

The Effect of Selected Bee Products on Adhesion and Biofilm of <i>Clostridioides difficile</i> Strains Belonging to Different Ribotypes
حسب: Dorota Wultańska, وآخرون
منشور في: (2022-10-01)

Rapid Classification of <i>Clostridioides difficile</i> Strains Using MALDI-TOF MS Peak-Based Assay in Comparison with PCR-Ribotyping
حسب: Adriana Calderaro, وآخرون
منشور في: (2021-03-01)

The Effect of Subinhibitory Concentration of Metronidazole on the Growth and Biofilm Formation on Toxigenic <i>Clostridioides difficile</i> Strains Belonging to Different Ribotypes
حسب: Dorota Wultańska, وآخرون
منشور في: (2023-10-01)

Role of the Alteration in Calcium Homeostasis in Cell Death Induced by <i>Clostridioides difficile</i> Toxin A and Toxin B
حسب: Katia Fettucciari, وآخرون
منشور في: (2023-08-01)

The Colonisation of Calves in Czech Large-Scale Dairy Farms by Clonally-Related <i>Clostridioides difficile</i> of the Sequence Type 11 Represented by Ribotypes 033 and 126
حسب: Martina Masarikova, وآخرون
منشور في: (2020-06-01)

Molecular epidemiological analyses of Clostridioides difficile isolates in a university hospital in Japan
حسب: Yukitaka Ito, وآخرون
منشور في: (2023-10-01)

Genetic Relatedness of 5-Year Isolates of <i>Clostridioides difficile</i> Polymerase Chain Reaction Ribotype 017 Strains in a Hospital
حسب: Jieun Kim, وآخرون
منشور في: (2021-10-01)

Exploring the Toxin-Mediated Mechanisms in <i>Clostridioides difficile</i> Infection
حسب: Evdokia Pourliotopoulou, وآخرون
منشور في: (2024-05-01)

Diagnostic Methods of <i>Clostridioides difficile</i> Infection and <i>Clostridioides difficile</i> Ribotypes in Studied Sample
حسب: Elena Novakova, وآخرون
منشور في: (2021-08-01)

The Environment, Farm Animals and Foods as Sources of <i>Clostridioides difficile</i> Infection in Humans
حسب: Declan Bolton, وآخرون
منشور في: (2023-03-01)

Automated web-based typing of Clostridioides difficile ribotypes via MALDI-TOF MS
حسب: Mario Blázquez-Sánchez, وآخرون
منشور في: (2025-07-01)

Ribotypes and antimicrobial susceptibility profiles of clinical Clostridioides difficile isolates: A multicenter, laboratory-based surveillance in Taiwan, 2019–2021
حسب: Chin-Shiang Tsai, وآخرون
منشور في: (2024-04-01)

Outbreak of Clostridioides difficile infection in Silesian district hospital
حسب: Klaudia T. Szarek, وآخرون
منشور في: (2023-06-01)

Baicalein and Berberine Inhibit the Growth and Virulence of <i>Clostridioides difficile</i>
حسب: Xue Yang, وآخرون
منشور في: (2025-07-01)

Occurrence of Clostridium difficile infections due to PCR ribotype 027 in Bucharest, Romania
حسب: Alexandru Rafila, وآخرون
منشور في: (2014-06-01)

An Update on <i>Clostridioides difficile</i> Binary Toxin
حسب: Adrián Martínez-Meléndez, وآخرون
منشور في: (2022-04-01)

Dominance of toxigenic Clostridioides difficile strains and the appearance of the emerging PCR ribotype 955 in hospitals in Silesia, Poland
حسب: Klaudia Szarek, وآخرون
منشور في: (2025-08-01)

Retrospective Definition of <i>Clostridioides difficile</i> PCR Ribotypes on the Basis of Whole Genome Polymorphisms: A Proof of Principle Study
حسب: Manisha Goyal, وآخرون
منشور في: (2020-12-01)

Whole Genome Sequencing Evidences High Rates of Relapse in <i>Clostridioides difficile</i> Infection Caused by the Epidemic Ribotype 106
حسب: Loreto Suárez-Bode, وآخرون
منشور في: (2023-01-01)

Efficacy of UV-C 254 nm Light and a Sporicidal Surface Disinfectant in Inactivating Spores from <i>Clostridioides difficile</i> Ribotypes In Vitro
حسب: Khald Blau, وآخرون
منشور في: (2024-11-01)

Biofilm Formation of <i>Clostridioides difficile</i>, Toxin Production and Alternatives to Conventional Antibiotics in the Treatment of CDI
حسب: Leon M. T. Dicks
منشور في: (2023-08-01)

Community-acquired fulminant Clostridioides (Clostridium) difficile infection by ribotype 027 isolate in Japan: a case report
حسب: Masayuki Hiraki, وآخرون
منشور في: (2021-06-01)

Emerging Clostridioides difficile strains belonging to PCR ribotype 955 in Serbia are distinct from metronidazole-resistant RT955 outbreak isolates from the UK
حسب: Predrag Stojanovic, وآخرون
منشور في: (2025-12-01)

A Colombian strain of Clostridioides difficile ribotype 002 induces a highly inflammatory response in a mouse infection model
حسب: Juan David Puerta-Arias, وآخرون
منشور في: (2025-12-01)

Domperidone Protects Cells from Intoxication with <i>Clostridioides difficile</i> Toxins by Inhibiting Hsp70-Assisted Membrane Translocation
حسب: Maria Braune-Yan, وآخرون
منشور في: (2023-06-01)

Characterisation and antibiotic susceptibility profile of Clostridioides (Clostridium) difficile isolated from chicken carcasses
حسب: Bingol Enver Baris, وآخرون
منشور في: (2020-08-01)

<i>Clostridioides difficile</i> from Fecally Contaminated Environmental Sources: Resistance and Genetic Relatedness from a Molecular Epidemiological Perspective
حسب: Khald Blau, وآخرون
منشور في: (2023-10-01)

Clostridioides difficile ribotypes 001 and 126 were predominant in Tehran healthcare settings from 2004 to 2018: a 14-year-long cross-sectional study
حسب: Masoumeh Azimirad, وآخرون
منشور في: (2020-01-01)

<i>Clostridioides difficile</i> and Gut Microbiota: From Colonization to Infection and Treatment
حسب: Patrizia Spigaglia
منشور في: (2024-07-01)

Systematic Evaluation of Parameters Important for Production of Native Toxin A and Toxin B from <i>Clostridioides difficile</i>
حسب: Aria Aminzadeh, وآخرون
منشور في: (2021-03-01)