Detection of residual <i>E. coli</i> and CHO<i></i>host-cell<i></i>DNA in recombinant proteins by qPCR

Production of recombinant proteins is a steadily growing industry in Russia and all over the world. Both producer and substance should be properly characterized and tested against all safety criteria. One of the mandatory requirements to the mentioned drugs is the assessment of the content of residu...

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Bibliographic Details

Published in:	Биопрепараты: Профилактика, диагностика, лечение
Main Author:	N. D. Yolshin
Format:	Article
Language:	Russian
Published:	Ministry of Health of the Russian Federation. Federal State Budgetary Institution «Scientific Centre for Expert Evaluation of Medicinal Products» 2018-02-01
Subjects:	определение остаточной днк клеток-продуцентов остаточная днк клеток хозяина qpcr днк cho qpcr днк e. coli выделение днк из субстанций рекомбинантных белков detection of residual dna-producing cells residual host-cell dna the dna qpcr cho host cell qpcr e. coli host-cell dna dna isolation from protein solutions
Online Access:	https://www.biopreparations.ru/jour/article/view/71