Methodological biases in observational hospital studies of COVID-19 treatment effectiveness: pitfalls and potential

IntroductionThis study aims to discuss and assess the impact of three prevalent methodological biases: competing risks, immortal-time bias, and confounding bias in real-world observational studies evaluating treatment effectiveness. We use a demonstrative observational data example of COVID-19 patie...

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التفاصيل البيبلوغرافية

الحاوية / القاعدة:	Frontiers in Medicine
المؤلفون الرئيسيون:	Oksana Martinuka, Derek Hazard, Hamid Reza Marateb, Marjan Mansourian, Miguel Ángel Mañanas, Sergio Romero, Manuel Rubio-Rivas, Martin Wolkewitz
التنسيق:	مقال
اللغة:	الإنجليزية
منشور في:	Frontiers Media S.A. 2024-03-01
الموضوعات:	competing risks confounding COVID-19 emulated trial immortal-time bias methodological bias
الوصول للمادة أونلاين:	https://www.frontiersin.org/articles/10.3389/fmed.2024.1362192/full