Generation of Induced Progenitor-like Cells from Mature Epithelial Cells Using Interrupted Reprogramming

Summary: A suitable source of progenitor cells is required to attenuate disease or affect cure. We present an âinterrupted reprogrammingâ strategy to generate âinduced progenitor-like (iPL) cellsâ using carefully timed expression of induced pluripotent stem cell reprogramming factors (Oct4, Sox2, Kl...

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Bibliographic Details

Published in:	Stem Cell Reports
Main Authors:	Li Guo, Golnaz Karoubi, Pascal Duchesneau, Maria V. Shutova, Hoon-Ki Sung, Peter Tonge, Christine Bear, Ian Rogers, Andras Nagy, Thomas K. Waddell
Format:	Article
Language:	English
Published:	Elsevier 2017-12-01
Online Access:	http://www.sciencedirect.com/science/article/pii/S2213671117304770