Maternal Age at Delivery Is Associated with an Epigenetic Signature in Both Newborns and Adults.

Offspring of older mothers are at increased risk of adverse birth outcomes, childhood cancers, type 1 diabetes, and neurodevelopmental disorders. The underlying biologic mechanisms for most of these associations remain obscure. One possibility is that maternal aging may produce lasting changes in th...

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Bibliographic Details
Published in:PLoS ONE
Main Authors: Christina A Markunas, Allen J Wilcox, Zongli Xu, Bonnie R Joubert, Sophia Harlid, Vijayalakshmi Panduri, Siri E Håberg, Wenche Nystad, Stephanie J London, Dale P Sandler, Rolv T Lie, Paul A Wade, Jack A Taylor
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0156361&type=printable