Dissecting the causal relationship between neuroticism and osteoarthritis: a univariable and multivariable Mendelian randomization study

BackgroundMental health has been found to be associated with risk of osteoarthritis (OA), but the causal relationship was not fully clarified.MethodsTwo-sample Mendelian randomization (MR) study was conducted to investigate the causal relationship between neuroticism (n = 329,821) and the two most f...

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Bibliographic Details

Published in:	Frontiers in Psychiatry
Main Authors:	Shuren Zhang, Junhui Ji, Zexia Zhang, Zhichao Cui, MeiHua Su
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2024-03-01
Subjects:	neuroticism osteoarthritis Mendelian randomization causal relationship single-nucleotide polymorphisms
Online Access:	https://www.frontiersin.org/articles/10.3389/fpsyt.2024.1333528/full