Unraveling the Metabolic Mechanisms and Novel Biomarkers of Vulvar Lichen Simplex Chronicus Using Skin Biopsy and Tape Stripping Samples

Background/Objectives: Lichen simplex chronicus (LSC) of the vulva is a chronic dermatologic disorder characterized by persistent pruritus, compulsive scratching, and progressive thickening of the vulvar skin. Currently, LSC diagnosis primarily relies on clinical presentation, with histopathological...

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Bibliographic Details

Published in:	Metabolites
Main Authors:	Tian He, Fanrui Xu, Jing Liang, Qing Feng, Dan Cheng, Linlin Xiao, Maoyu Liu, Xuerui Zhang, Xin Wang, Yang Yang, Dan Zhu, Sergey Tumanov, Richard D. Cannon, Ting-Li Han, Shufang Chang
Format:	Article
Language:	English
Published:	MDPI AG 2025-08-01
Subjects:	vulvar lichen simplex chronicus (VLSC) tape stripping skin biopsy metabolomics TRPV1 20-HETE
Online Access:	https://www.mdpi.com/2218-1989/15/9/566