A ternary-code DNA methylome atlas of mouse tissues

Abstract Background DNA cytosine modifications, including 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC), are key epigenetic regulators with distinct functions. Dissecting the ternary code (C, 5mC, 5hmC) across tissues and cell types remains a critical priority due to the limitations of t...

Full description

Bibliographic Details
Published in:Genome Biology
Main Authors: Sol Moe Lee, David C. Goldberg, Cameron Cloud, Jared B. Parker, Christopher Krapp, Christian E. Loo, Elliot Kim, Ivan Zhao, Chengcheng Jin, Rishi Porecha, Marisa S. Bartolomei, Rahul M. Kohli, Wanding Zhou
Format: Article
Language:English
Published: BMC 2025-10-01
Subjects:
DNA methylation
Hydroxymethylation
Epigenetics
Mouse
Cell identity
Aging
Online Access:https://doi.org/10.1186/s13059-025-03808-y

Internet

https://doi.org/10.1186/s13059-025-03808-y

Similar Items