TCR-T cell therapy for solid tumors: challenges and emerging solutions

With the use of T cell receptor T cells (TCR-T cells) and chimeric antigen receptor T cells (CAR-T cells), T-cell immunotherapy for cancer has advanced significantly in recent years. CAR-T cell therapy has demonstrated extraordinary success when used to treat hematologic malignancies. Nevertheless,...

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Bibliographic Details

Published in:	Frontiers in Pharmacology
Main Authors:	Wanjun He, Kai Cui, Muhammad Asad Farooq, Na Huang, Songshan Zhu, Dan Jiang, Xiqian Zhang, Jian Chen, Yinxia Liu, Guangxian Xu
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-03-01
Subjects:	adoptive cell therapy immunotherapy solid tumor TCR TCR-T cell
Online Access:	https://www.frontiersin.org/articles/10.3389/fphar.2025.1493346/full