Progesterone Enhances Niraparib Efficacy in Ovarian Cancer by Promoting Palmitoleic-Acid-Mediated Ferroptosis

Poly (adenosine 5′-diphosphate-ribose) polymerase inhibitors (PARPi) are increasingly important in the treatment of ovarian cancer. However, more than 40% of BRCA1/2-deficient patients do not respond to PARPi, and BRCA wild-type cases do not show obvious benefit. In this study, we demonstrated that...

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出版年:	Research
主要な著者:	Nayiyuan Wu, Xiu Zhang, Chao Fang, Miaochen Zhu, Zhibin Wang, Lian Jian, Weili Tan, Ying Wang, He Li, Xuemeng Xu, Yujuan Zhou, Tang-Yuan Chu, Jing Wang, Qianjin Liao
フォーマット:	論文
言語:	英語
出版事項:	American Association for the Advancement of Science (AAAS) 2024-01-01
オンライン･アクセス:	https://spj.science.org/doi/10.34133/research.0371