The Potential Therapeutic Applications of Natural Products in the Oxidative Stress-Related MVA Pathway: Focus on HMGCR

This review explores the therapeutic promise of natural compounds in modulating 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR), a key enzyme in cholesterol synthesis. HMGCR dysregulation is implicated in dyslipidemia, cardiovascular disease, and cancer, conditions linked to oxidative stress...

Full description

Bibliographic Details
Published in:Antioxidants
Main Author: Yu-Ning Teng
Format: Article
Language:English
Published: MDPI AG 2025-08-01
Subjects:
Online Access:https://www.mdpi.com/2076-3921/14/8/1001