Heparin-based versus bivalirudin-based anticoagulation in pediatric extracorporeal membrane oxygenation: A systematic review

IntroductionOptimal anticoagulation therapy is essential for the prevention of thrombotic and hemorrhagic complications in pediatric patients supported with extracorporeal membrane oxygenation (ECMO). Recent data have demonstrated bivalirudin has the potential to surpass and replace heparin as the a...

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Bibliographic Details

Published in:	Frontiers in Medicine
Main Authors:	Carlos A. Valdes, Omar M. Sharaf, Mark S. Bleiweis, Jeffrey P. Jacobs, Mohammed Mumtaz, Ramy M. Sharaf, Eric I. Jeng, Giles J. Peek
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-03-01
Subjects:	anticoagulation bivalirudin extracorporeal membrane oxygenation (ECMO) pediatric direct thrombin inhibitor
Online Access:	https://www.frontiersin.org/articles/10.3389/fmed.2023.1137134/full