YTHDF1 Regulates Tumorigenicity and Cancer Stem Cell-Like Activity in Human Colorectal Carcinoma

YTH N6-methyladenosine (m6A) RNA binding protein 1 (YTHDF1) is a core factor in RNA methylation modification. Recent studies have shown that m6A is closely related to multiple tumors, thus YTHDF1 may also play a role in tumorigenesis. This study, aimed to explore the role of YTHDF1 in the colorectal...

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Bibliographic Details

Published in:	Frontiers in Oncology
Main Authors:	Yang Bai, Chunxing Yang, Runliu Wu, Lihua Huang, Shenlei Song, Wanwan Li, Peichen Yan, Changwei Lin, Daojiang Li, Yi Zhang
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2019-05-01
Subjects:	CRC YTHDF1 CNV tumorigenicity CSC Wnt/β-catenin pathway
Online Access:	https://www.frontiersin.org/article/10.3389/fonc.2019.00332/full