Expression of LINE-1 elements is required for preimplantation development and totipotency

Transposable elements, long considered genomic intruders, have been found to play significant and intriguing roles during early embryonic development based on the paradigm shift that has undergone in recent years. Long interspersed element-1 (LINE-1) is the predominant class of retrotransposons with...

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Bibliographic Details

Published in:	Genes and Diseases
Main Authors:	Ru Ma, Nan Xiao, Na Liu
Format:	Article
Language:	English
Published:	KeAi Communications Co., Ltd. 2025-09-01
Subjects:	Embryonic stem cells Epigenetic LINE-1 Preimplantation development Totipotent Transposable elements
Online Access:	http://www.sciencedirect.com/science/article/pii/S2352304225000443