Ethyl acetate extract of Ruta graveolens: a specific and potent inhibitor against the drug-resistant EGFR_T790M mutant in NSCLC

Lung cancer, the second leading cause of cancer mortality, requires the development of novel therapeutic strategies due to emerging drug resistance and toxicity. With this objective, the present work explored the therapeutic potential of R. graveolens leaf extracts against EGFR_T790M-mediated drug r...

詳細記述

書誌詳細

出版年:	Frontiers in Pharmacology
主要な著者:	Vikas Kumar, Leena Chauhan, Deepa Singh, Akash Kumar, Rajkumar Kulandaisamy, Tushar Kushwaha, Kamal Baswal, Rajan Singh, Saroj Kumar, Shivajirao L. Gholap, P. Hariprasad, S. Babu Dadinaboyina, Jagadeshwar R. Thota, Deepak Sehgal, Mohan B. Appaiahgari, Krishna K. Inampudi
フォーマット:	論文
言語:	英語
出版事項:	Frontiers Media S.A. 2025-04-01
主題:	Lung cancer NSCLC EGFR_T790M mutation Ruta graveolens ethyl acetate extract
オンライン･アクセス:	https://www.frontiersin.org/articles/10.3389/fphar.2025.1570108/full