The mitochondria-targeted antioxidants and remote kidney preconditioning ameliorate brain damage through kidney-to-brain cross-talk.

BACKGROUND: Many ischemia-induced neurological pathologies including stroke are associated with high oxidative stress. Mitochondria-targeted antioxidants could rescue the ischemic organ by providing specific delivery of antioxidant molecules to the mitochondrion, which potentially suffers from oxida...

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Bibliographic Details

Published in:	PLoS ONE
Main Authors:	Denis N Silachev, Nikolay K Isaev, Irina B Pevzner, Ljubava D Zorova, Elena V Stelmashook, Svetlana V Novikova, Egor Y Plotnikov, Vladimir P Skulachev, Dmitry B Zorov
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2012-01-01
Online Access:	http://europepmc.org/articles/PMC3522699?pdf=render