TimeNorm: a novel normalization method for time course microbiome data

Metagenomic time-course studies provide valuable insights into the dynamics of microbial systems and have become increasingly popular alongside the reduction in costs of next-generation sequencing technologies. Normalization is a common but critical preprocessing step before proceeding with downstre...

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Bibliographic Details

Published in:	Frontiers in Genetics
Main Authors:	Qianwen Luo, Meng Lu, Hamza Butt, Nicholas Lytal, Ruofei Du, Hongmei Jiang, Lingling An
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2024-09-01
Subjects:	microbiome metagenomics normalization time-course dominant features longitudinal
Online Access:	https://www.frontiersin.org/articles/10.3389/fgene.2024.1417533/full