Kinesin-7 CENP-E in tumorigenesis: Chromosome instability, spindle assembly checkpoint, and applications

Kinesin motors are a large family of molecular motors that walk along microtubules to fulfill many roles in intracellular transport, microtubule organization, and chromosome alignment. Kinesin-7 CENP-E (Centromere protein E) is a chromosome scaffold-associated protein that is located in the corona l...

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Bibliographic Details

Published in:	Frontiers in Molecular Biosciences
Main Authors:	Yu-Hao Yang, Ya-Lan Wei, Zhen-Yu She
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2024-03-01
Subjects:	kinesin CENP-E chromosome instability cancer aneuploidy tumorigenesis
Online Access:	https://www.frontiersin.org/articles/10.3389/fmolb.2024.1366113/full