Stress-inducible phosphoprotein 1 (STIP1) is a critical stemness regulator in mouse embryonic stem cells and early mammalian development

Abstract Proteostasis, maintained by a network of molecular chaperones, plays a central role in cell biology, and has emerged as a critical mechanism underlying pluripotency and development. The stress-inducible phosphoprotein 1 (STIP1) is a co-chaperone essential for proteostasis. STIP1 knockout ca...

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Bibliographic Details

Published in:	Communications Biology
Main Authors:	Camila Felix de Lima Fernandes, Marilene Hohmuth Lopes, Maria Clara da Silva Souza, Samuel Ribeiro Soares, Jenny Andrea Arévalo-Romero, Rachel E. Lackie, Bárbara Paranhos Coelho, João Pedro Alves de Araújo, Jacqueline Marcia Boccacino, Rebeca Piatniczka Iglesia, Maria Isabel Melo-Escobar, Mariana Brandão Prado, Marcelo Falchetti, Frederico Moraes Ferreira, Helder Nakaya, Tiago Góss dos Santos, Edroaldo Lummertz da Rocha, Flávio H. Beraldo, Vania F. Prado, Marco A. M. Prado
Format:	Article
Language:	English
Published:	Nature Portfolio 2025-08-01
Online Access:	https://doi.org/10.1038/s42003-025-08763-9