Phenylalanine ammonia-lyase through evolution: A bioinformatic approach

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Phenylalanine ammonia-lyase (PAL) is the first entry enzyme of the phenylpropanoid pathway that converts phenylalanine to cinnamic acid which is the precursor of various secondary metabolites. PAL is recently formulated for phenylketonuric patients in pegylated forms; therefore, screening a PAL with...

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Bibliographic Details
Published in:Trends in Pharmaceutical Sciences
Main Author: Shiva Hemmati
Format: Article
Language:English
Published: Shiraz University of Medical Sciences 2015-03-01
Subjects:
Phenylalanine ammonia lyase
Phylogenetic tree
Bioinformatic
Evolution
Phenylketonuria
Online Access:http://tips.sums.ac.ir/index.php/TiPS/article/view/12/7

Internet

http://tips.sums.ac.ir/index.php/TiPS/article/view/12/7

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