The formation of the ‘footprint of death’ as a mechanism for generating large substrate-bound extracellular vesicles that mark the site of cell death

Abstract Apoptotic cells communicate to phagocytic cells through releasing soluble factors and apoptotic cell-derived extracellular vesicles. However, whether there are additional factors that remain attached at the site of cell death to signal to phagocytic cells is currently unknown. Here we show...

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Bibliographic Details

Published in:	Nature Communications
Main Authors:	Stephanie F. Rutter, Taeyoung Kang, Gemma F. Ryan, Bo Shi, Caitlin L. Vella, Pradeep Rajasekhar, Sean W. Cutter, Amy L. Hodge, Dilara C. Ozkocak, Ching-Seng Ang, Julian Ratcliffe, Katrina J. Binger, Pamali Foneska, Suresh Mathivanan, Niall D. Geoghegan, Kelly L. Rogers, Michael F. Olson, Georgia K. Atkin-Smith, Ivan K. H. Poon
Format:	Article
Language:	English
Published:	Nature Portfolio 2025-10-01
Online Access:	https://doi.org/10.1038/s41467-025-64206-3