TGF-β signalling limits effector function capacity of NK cell anti-tumour immunity in human bladder cancerResearch in context

Summary: Background: Natural killer (NK) cells are important innate immunity players and have unique abilities to recognize and eliminate cancer cells, particularly in settings of antibody-opsonization and antibody-dependant cellular cytotoxicity (ADCC). However, NK cell-based responses in bladder...

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Bibliographic Details

Published in:	EBioMedicine
Main Authors:	Joshua K.M. Wong, Timothy R. McCulloch, Louisa Alim, Natacha Omer, Ahmed M. Mehdi, Zewen Kelvin Tuong, Alexis Bonfim-Melo, Eric Chung, Alice Nicol, Fiona Simpson, Handoo Rhee, Gustavo Rodrigues Rossi, Fernando Souza-Fonseca-Guimaraes
Format:	Article
Language:	English
Published:	Elsevier 2024-06-01
Subjects:	ADCC NK cells TGF-β CD16 Bladder cancer
Online Access:	http://www.sciencedirect.com/science/article/pii/S2352396424002111