Single-cell insights: pioneering an integrated atlas of chromatin accessibility and transcriptomic landscapes in diabetic cardiomyopathy

Abstract Background Diabetic cardiomyopathy (DCM) poses a growing health threat, elevating heart failure risk in diabetic individuals. Understanding DCM is crucial, with fibroblasts and endothelial cells playing pivotal roles in driving myocardial fibrosis and contributing to cardiac dysfunction. Ad...

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Bibliographic Details

Published in:	Cardiovascular Diabetology
Main Authors:	Qiang Su, Wanzhong Huang, Yuan Huang, Rixin Dai, Chen Chang, Qiu-Yan Li, Hao Liu, Zhenhao Li, Yuxiang Zhao, Qiang Wu, Di-Guang Pan
Format:	Article
Language:	English
Published:	BMC 2024-04-01
Subjects:	DCM scRNA-seq scATAC-seq Cardiomyocytes Fibroblasts Endothelial
Online Access:	https://doi.org/10.1186/s12933-024-02233-y