Rational Development of a Carrier-Free Dry Powder Inhalation Formulation for Respiratory Viral Infections via Quality by Design: A Drug-Drug Cocrystal of Favipiravir and Theophylline

Formulating pharmaceutical cocrystals as inhalable dosage forms represents a unique niche in effective management of respiratory infections. Favipiravir, a broad-spectrum antiviral drug with potential pharmacological activity against SARS-CoV-2, exhibits a low aqueous solubility. An ultra-high oral...

وصف كامل

التفاصيل البيبلوغرافية
الحاوية / القاعدة:Pharmaceutics
المؤلفون الرئيسيون: Si Nga Wong, Jingwen Weng, Ignatius Ip, Ruipeng Chen, Richard Lakerveld, Richard Telford, Nicholas Blagden, Ian J. Scowen, Shing Fung Chow
التنسيق: مقال
اللغة:الإنجليزية
منشور في: MDPI AG 2022-01-01
الموضوعات:
cocrystal screening
inhalable cocrystal
drug-drug cocrystal
antiviral cocrystal
reformulation
quality-by-design
الوصول للمادة أونلاين:https://www.mdpi.com/1999-4923/14/2/300

الانترنت

https://www.mdpi.com/1999-4923/14/2/300

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