Effects of strategic white matter hyperintensities of cholinergic pathways on basal forebrain volume in patients with amyloid-negative neurocognitive disorders

Abstract Background The cholinergic neurotransmitter system is crucial to cognitive function, with the basal forebrain (BF) being particularly susceptible to Alzheimer’s disease (AD) pathology. However, the interaction of white matter hyperintensities (WMH) in cholinergic pathways and BF atrophy wit...

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Bibliographic Details

Published in:	Alzheimer’s Research & Therapy
Main Authors:	Ye Eun Kim, Jae-Sung Lim, Chong Hyun Suh, Hwon Heo, Jee Hoon Roh, E-nae Cheong, Yoojin Lee, Jae Woo Kim, Jae-Hong Lee
Format:	Article
Language:	English
Published:	BMC 2024-08-01
Subjects:	White matter hyperintensities Basal forebrain Neurodegeneration Cholinergic pathway Amyloid-negative, vascular cognitive impairment
Online Access:	https://doi.org/10.1186/s13195-024-01536-2