Crosstalk between thyroid hormone receptor and liver X receptor in the regulation of selective Alzheimer's disease indicator-1 gene expression.

Selective Alzheimer's disease (AD) indicator 1 (Seladin-1) has been identified as a gene down-regulated in the degenerated lesions of AD brain. Up-regulation of Seladin-1 reduces the accumulation of β-amyloid and neuronal death. Thyroid hormone (TH) exerts an important effect on the development...

Full description

Bibliographic Details

Published in:	PLoS ONE
Main Authors:	Emi Ishida, Koshi Hashimoto, Shuichi Okada, Tetsurou Satoh, Masanobu Yamada, Masatomo Mori
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2013-01-01
Online Access:	http://europepmc.org/articles/PMC3554671?pdf=render