Enantioseparation of <i>P</i>-Stereogenic 1-Adamantyl Arylthiophosphonates and Their Stereospecific Transformation to 1-Adamantyl Aryl-<i>H</i>-phosphinates

A focused library of 1-adamantyl arylthiophosphonates was prepared in racemic form. An enantioseparation method was developed for <i>P</i>-stereogenic thiophosphonates using (<i>S</i>)-1-phenylethylamine as the resolving agent. Under optimized conditions, three out of the fiv...

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Bibliographic Details

Published in:	Molecules
Main Authors:	Bence Varga, Levente Buna, Daniella Vincze, Tamás Holczbauer, Béla Mátravölgyi, Elemér Fogassy, György Keglevich, Péter Bagi
Format:	Article
Language:	English
Published:	MDPI AG 2023-02-01
Subjects:	thiophosphonate <i>H</i>-phosphinate <i>P</i>-stereogenic enantioseparation organocatalysis
Online Access:	https://www.mdpi.com/1420-3049/28/4/1584