Exogenous melatonin alleviates premature ovarian failure by regulating granulosa cell autophagy

Abstract Premature ovarian failure (POF) is a disease closely related to the apoptosis of granulosa cells (GCs) in the follicle. In this study, exogenous melatonin (Mel) was used to interfere with POF model mice, so as to provide reference for Mel prevention and treatment of POF. Mel could promote e...

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Bibliographic Details

Published in:	npj Regenerative Medicine
Main Authors:	Guang-hu Zhou, Ye-fei He, Hai-ling Wang, Yi-bo Lv, Yi-mei Cong, Zhen-long Sun, Xiao-wen Jiang, Wen-hui Yu
Format:	Article
Language:	English
Published:	Nature Portfolio 2025-07-01
Online Access:	https://doi.org/10.1038/s41536-025-00422-1