Beneficial Impacts of Incorporating the Non-Natural Amino Acid Azulenyl-Alanine into the Trp-Rich Antimicrobial Peptide buCATHL4B

Antimicrobial peptides (AMPs) present a promising scaffold for the development of potent antimicrobial agents. Substitution of tryptophan by non-natural amino acid Azulenyl-Alanine (AzAla) would allow studying the mechanism of action of AMPs by using unique properties of this amino acid, such as abi...

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發表在:	Biomolecules
Main Authors:	Areetha R. D’Souza, Matthew R. Necelis, Alona Kulesha, Gregory A. Caputo, Olga V. Makhlynets
格式:	Article
語言:	英语
出版:	MDPI AG 2021-03-01
主題:	antimicrobial peptides fluorescence lipid binding buCATHL4B non-natural amino acids protease resistance
在線閱讀:	https://www.mdpi.com/2218-273X/11/3/421