Atom Economical Multi-Substituted Pyrrole Synthesis from Aziridine

Multi-substituted pyrroles are synthesized from regiospecific aziridine ring-opening and subsequent intramolecular cyclization with a carbonyl group at the <i>γ</i>-position in the presence of Lewis acid or protic acid. This method is highly atom economical where all the atoms of the rea...

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Bibliographic Details
Published in:Molecules
Main Authors: Lingamurthy Macha, Ranjith Jala, Sang-Yun Na, Hyun-Joon Ha
Format: Article
Language:English
Published: MDPI AG 2022-10-01
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Online Access:https://www.mdpi.com/1420-3049/27/20/6869