KRAS G12C mutation in NSCLC in a small genetic center: insights into sotorasib therapy response potential

Abstract Lung cancer remains a significant health challenge, characterized by aberrant tissue growth within the pulmonary system. Early carcinogenic events often involve genomic instability and the emergence of a mutator phenotype. In this study, we aimed to explore the mutator phenotype in 89 patie...

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Bibliographic Details

Published in:	Scientific Reports
Main Authors:	Metin Eser, Gulam Hekimoglu, Murat Hakki Yarar, Sezin Canbek, Melike Ozcelik
Format:	Article
Language:	English
Published:	Nature Portfolio 2024-11-01
Subjects:	KRAS G12C mutation Non-small-cell lung cancer Sotorasib
Online Access:	https://doi.org/10.1038/s41598-024-75208-4