Progress on 3-Nitropropionic Acid Derivatives
3-Nitropropionic acid (3-NPA) is a deadly neurotoxic nitroalkane found in numerous fungi and leguminous plants. 3-NPA, known as an antimetabolite of succinate, irreversibly inhibits succinate dehydrogenase and disrupts mitochondrial oxidative phosphorylation. Its utility in modeling Huntington’s dis...
| Published in: | Biomolecules |
|---|---|
| Main Authors: | , , |
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2025-07-01
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| Subjects: | |
| Online Access: | https://www.mdpi.com/2218-273X/15/8/1066 |