Progress on 3-Nitropropionic Acid Derivatives

3-Nitropropionic acid (3-NPA) is a deadly neurotoxic nitroalkane found in numerous fungi and leguminous plants. 3-NPA, known as an antimetabolite of succinate, irreversibly inhibits succinate dehydrogenase and disrupts mitochondrial oxidative phosphorylation. Its utility in modeling Huntington’s dis...

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发表在:Biomolecules
Main Authors: Meng-Lin Feng, Zheng-Hui Li, Bao-Bao Shi
格式: 文件
语言:英语
出版: MDPI AG 2025-07-01
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在线阅读:https://www.mdpi.com/2218-273X/15/8/1066

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