Genetic Insights Into the Role of Cathepsins in Alzheimer's Disease, Parkinson's Disease, and Amyotrophic Lateral Sclerosis: Evidence From Mendelian Randomization Study

Abstract Background Previous studies have confirmed the significant role of cathepsins in the development of neurodegenerative diseases. We aimed to determine whether genetically predicted 10 cathepsins may have a causal effect on Alzheimer's disease (AD), Parkinson's disease (PD), and amy...

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Bibliographic Details

Published in:	Brain and Behavior
Main Authors:	Yanhong Jiang, Wenhui Fan, Yaxin Li, Hua Xue
Format:	Article
Language:	English
Published:	Wiley 2025-01-01
Subjects:	Alzheimer's disease amyotrophic lateral sclerosis cathepsins mendelian randomization Parkinson's disease
Online Access:	https://doi.org/10.1002/brb3.70207