Detection of Cleaved Stx2a in the Blood of STEC-Infected Patients

Typical hemolytic uremic syndrome (HUS) is mainly caused by Shiga toxin-producing <i>Escherichia coli</i> (STEC) releasing Shiga toxin 2 (Stx2). Two different structures of this AB5 toxin have been described: uncleaved, with intact B and A chains, and cleaved, with intact B and a nicked...

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Bibliographic Details
Published in:Toxins
Main Authors: Elisa Varrone, Domenica Carnicelli, Xiaohua He, Marco Grasse, Karin Stampfer, Silke Huber, Sára Kellnerová, Pier Luigi Tazzari, Francesca Ricci, Paola Paterini, Gianluigi Ardissino, Stefano Morabito, Dorothea Orth-Höller, Reinhard Würzner, Maurizio Brigotti
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Subjects:
hemolytic uremic syndrome
cleaved Shiga toxin 2a
Shiga toxin-producing <i>Escherichia coli</i>
Online Access:https://www.mdpi.com/2072-6651/15/12/690

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https://www.mdpi.com/2072-6651/15/12/690

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