Propofol Mediated Protection of the Brain From Ischemia/Reperfusion Injury Through the Regulation of Microglial Connexin 43

Cerebral ischemia/reperfusion (I/R) injury is a serious condition that leads to increased apoptosis of microglial and neurons in the brain. In this study, we identified that Cx43 expression level is significantly increased in the microglial cells during I/R injury. Using an in vitro model (hypoxia/r...

Full description

Bibliographic Details

Published in:	Frontiers in Cell and Developmental Biology
Main Authors:	Tingting Zhang, Yanyan Wang, Qin Xia, Zhiyi Tu, Jiajun Sun, Qi Jing, Pei Chen, Xuan Zhao
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2021-06-01
Subjects:	Connexin 43 ischemia/reperfusion injury microglia propofol apoptosis
Online Access:	https://www.frontiersin.org/articles/10.3389/fcell.2021.637233/full