Life-threatening COVID-19 in a thymoma patient with anti-interferon-α autoantibodies

Neutralizing anti-interferon (IFN)-α autoantibodies can lead to immune dysregulation, potentially resulting in critical coronavirus disease 2019 (COVID-19). We report a case presenting with severe COVID-19 who was subsequently diagnosed to have thymoma and neutralizing anti-IFN-α autoantibodies.

Bibliographic Details

Published in:	Journal of Microbiology, Immunology and Infection
Main Authors:	Yu-Shan Shih, Wan-Ting Tsai, Bei-Chia Guo, Aristine Cheng, Jann-Tay Wang
Format:	Article
Language:	English
Published:	Elsevier 2025-06-01
Subjects:	Anti-IFN-α autoantibodies Type 1 interferons Thymoma Critical COVID-19 Viral infections
Online Access:	http://www.sciencedirect.com/science/article/pii/S1684118225000350