An integrated strategy for comprehensive characterization of metabolites and metabolic profiles of bufadienolides from Venenum Bufonis in rats

Comprehensive characterization of metabolites and metabolic profiles in plasma has considerable significance in determining the efficacy and safety of traditional Chinese medicine (TCM) in vivo. However, this process is usually hindered by the insufficient characteristic fragments of metabolites, ub...

Full description

Bibliographic Details

Published in:	Journal of Pharmaceutical Analysis
Main Authors:	Wen-Long Wei, Hao-Jv Li, Wen-Zhi Yang, Hua Qu, Zhen-Wei Li, Chang-Liang Yao, Jin-Jun Hou, Wan-Ying Wu, De-An Guo
Format:	Article
Language:	English
Published:	Elsevier 2022-02-01
Subjects:	Metabolic profiles Extension-mass defect filter Multidimensional data acquiring Metabolic network prediction Bufadienolides of Venenum Bufonis
Online Access:	http://www.sciencedirect.com/science/article/pii/S2095177921000186